A Novel Phage-Library-Selected Peptide Inhibits Human TNF-α Binding to Its Receptors

We report the identification of a new human tumor necrosis factor-alpha (TNF-α) specific peptide selected by competitive panning of a phage library. Competitive elution of phages was obtained using the monoclonal antibody adalimumab, which neutralizes pro-inflammatory processes caused by over-produc...

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Detalles Bibliográficos
Autores principales: Brunetti, Jlenia, Lelli, Barbara, Scali, Silvia, Falciani, Chiara, Bracci, Luisa, Pini, Alessandro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271742/
https://www.ncbi.nlm.nih.gov/pubmed/24896264
http://dx.doi.org/10.3390/molecules19067255

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271742/
https://www.ncbi.nlm.nih.gov/pubmed/24896264
http://dx.doi.org/10.3390/molecules19067255

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