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A Novel Phage-Library-Selected Peptide Inhibits Human TNF-α Binding to Its Receptors
We report the identification of a new human tumor necrosis factor-alpha (TNF-α) specific peptide selected by competitive panning of a phage library. Competitive elution of phages was obtained using the monoclonal antibody adalimumab, which neutralizes pro-inflammatory processes caused by over-produc...
Autores principales: | Brunetti, Jlenia, Lelli, Barbara, Scali, Silvia, Falciani, Chiara, Bracci, Luisa, Pini, Alessandro |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271742/ https://www.ncbi.nlm.nih.gov/pubmed/24896264 http://dx.doi.org/10.3390/molecules19067255 |
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