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Synthesis of Caffeic Acid Amides Bearing 2,3,4,5-Tetra-hydrobenzo[b][1,4]dioxocine Moieties and Their Biological Evaluation as Antitumor Agents

A series of caffeic acid amides D(1)-D(17) bearing 2,3,4,5-tetrahydrobenzo-[b][1,4]dioxocine units has been synthesized and their biological activities evaluated for potential antiproliferative and EGFR inhibitory activity. Of all the compounds studied, compound D(9) showed the most potent inhibitor...

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Detalles Bibliográficos
Autores principales: Yuan, Ji-Wen, Qiu, Han-Yue, Wang, Peng-Fei, Makawana, Jigar A., Yang, Yong-An, Zhang, Fei, Yin, Yong, Lin, Jie, Wang, Zhong-Chang, Zhu, Hai-Liang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271756/
https://www.ncbi.nlm.nih.gov/pubmed/24896265
http://dx.doi.org/10.3390/molecules19067269