Cargando…

Synthesis of Caffeic Acid Amides Bearing 2,3,4,5-Tetra-hydrobenzo[b][1,4]dioxocine Moieties and Their Biological Evaluation as Antitumor Agents

A series of caffeic acid amides D(1)-D(17) bearing 2,3,4,5-tetrahydrobenzo-[b][1,4]dioxocine units has been synthesized and their biological activities evaluated for potential antiproliferative and EGFR inhibitory activity. Of all the compounds studied, compound D(9) showed the most potent inhibitor...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yuan, Ji-Wen, Qiu, Han-Yue, Wang, Peng-Fei, Makawana, Jigar A., Yang, Yong-An, Zhang, Fei, Yin, Yong, Lin, Jie, Wang, Zhong-Chang, Zhu, Hai-Liang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2014
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271756/ https://www.ncbi.nlm.nih.gov/pubmed/24896265 http://dx.doi.org/10.3390/molecules19067269

Ejemplares similares

3,3,4,4-Tetrafluoro-2,3,4,5-tetrahydro-1,6-benzodioxocine-8-carbaldehyde
por: Zeng, Zhuo, et al.
Publicado: (2010)

2,3,4,5-Tetrafluorobenzoic acid–4,4′-bipyridine (2/1)
por: Zhu, Xiaohui
Publicado: (2009)

4-Acetyl-2,3,4,5-tetrahydro-1H-1,4-benzodiazepine
por: Zhao, Qing-Jie, et al.
Publicado: (2008)

Design, Synthesis, and Bioactivities of Novel Trifluoromethyl Pyrimidine Derivatives Bearing an Amide Moiety
por: Lan, Wenjun, et al.
Publicado: (2022)

N-[(4-Carbamoylphenyl)carbamothioyl]-2,3,4,5-tetrafluorobenzamide
por: Zhang, Li-Dan, et al.
Publicado: (2011)

tert-Butylammonium 2,3,4,5-tetrachloro-6-methoxycarbonylbenzoate
por: Li, Jian, et al.
Publicado: (2008)

Design, Synthesis and Antitumor Activity of Novel link-bridge and B-Ring Modified Combretastatin A-4 (CA-4) Analogues as Potent Antitubulin Agents
por: Duan, Yong-Tao, et al.
Publicado: (2016)

4,5,6,7-Tetrabromo-1,1,3-trimethyl-3-(2,3,4,5-tetrabromophenyl)indane
por: Konstantinov, Alex, et al.
Publicado: (2008)

4-Methyl-2-oxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine-5-carbaldehyde
por: Ravichandran, K., et al.
Publicado: (2009)

Discovery of New Apoptosis-Inducing Agents for Breast Cancer Based on Ethyl 2-Amino-4,5,6,7-Tetra Hydrobenzo[b]Thiophene-3-Carboxylate: Synthesis, In Vitro, and In Vivo Activity Evaluation
por: Gad, Emad M., et al.
Publicado: (2020)

Methyl 4-{[6-(4-bromophenyl)-3-oxo-2,3,4,5-tetrahydropyridazin-4-yl]methyl}benzoate
por: Bortoluzzi, Adailton J., et al.
Publicado: (2011)

Tetramethyl 1,1,2-triphenyl-2H-1λ(5)-phosphole-2,3,4,5-tetracarboxylate
por: Krawczyk, Krzysztof K., et al.
Publicado: (2010)

5-Chloroacetyl-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
por: Ravichandran, K., et al.
Publicado: (2009)

Crystal structure of 2,2,4-trimethyl-2,3,4,5-tetrahydro-1H-benzo[b][1,4]diazepine hemihydrate
por: Ezhilarasi, K. S., et al.
Publicado: (2015)

[(2R,3S,5R)-3-Acetoxy-5-(5-formyl-2,4-dioxo-1,2,3,4-tetrahydropyrimidin-1-yl)-2,3,4,5-tetrahydrofuran-2-yl]methyl acetate
por: Jia, Xue-Fei, et al.
Publicado: (2011)

3-(2-Oxo-2,3,4,5-tetrahydrofuran-3-yl)-1-benzofuran-2-carbonitrile
por: Okuda, Kensuke, et al.
Publicado: (2012)

Synthesis and Antifungal Activity of Pyrimidine Derivatives Containing an Amide Moiety
por: Wu, Wenneng, et al.
Publicado: (2021)

Crystal structure of bis(μ-2,3,4,5-tetrafluorobenzoato-κ(2) O:O′)bis[(1,10-phenanthroline-κ(2) N:N′)(2,3,4,5-tetrafluorobenzoato-κO)copper(II)] dihydrate
por: Sun, Junshan
Publicado: (2014)

Methanodibenzo[b,f][1,5]dioxocins as Novel Glutaminase Inhibitor with Anti-Glioblastoma Potential
por: Murugesan, Akshaya, et al.
Publicado: (2023)

2-Ethoxymethyl-6-ethyl-2,3,4,5-tetrahydro-1,2,4-triazine-3,5-dione
por: El-Brollosy, Nasser R., et al.
Publicado: (2012)

5-Dichloroacetyl-4-methyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one hemihydrate
por: Ravichandran, K., et al.
Publicado: (2009)

2,2,4-Trimethyl-5-(4-tolylsulfonyl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepine
por: Ravichandran, K., et al.
Publicado: (2009)

2-Chloro-1-(2,4,4-trimethyl-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-1-yl)ethanone
por: Thiruselvam, V., et al.
Publicado: (2013)

Pentafluorophenyl (3R,4R,5S)-5-{[(3R,4R,5S)-5-azidomethyl-3,4-dimethoxy-2,3,4,5-tetrahydrofuran-3-carboxamido]methyl}-3,4-dimethoxy-2,3,4,5-tetrahydrofuran-3-carboxylate
por: Simone, Michela I., et al.
Publicado: (2010)

Synthesis and evaluation of antitumor activities of novel chiral 1,2,4-triazole Schiff bases bearing γ-butenolide moiety
por: Li, Xiang, et al.
Publicado: (2012)

Design, Synthesis, and Antifungal Activity of Novel 1,2,4-Triazolo[4,3-c]trifluoromethylpyrimidine Derivatives Bearing the Thioether Moiety
por: Liu, Chunyi, et al.
Publicado: (2022)

Ethyl 2-hydroxy-5-oxo-4-phenyl-2,3,4,5-tetrahydropyrano[3,2-c]chromene-2-carboxylate
por: Zhang, Wei, et al.
Publicado: (2009)

Crystal structure of 1,1,2,2-tetramethyl-1,2-bis(2,3,4,5-tetramethylcyclopenta-2,4-dien-1-yl)disilane
por: Godemann, Christian, et al.
Publicado: (2015)

Borylated 2,3,4,5-Tetrachlorophthalimide and Their 2,3,4,5-Tetrachlorobenzamide Analogues: Synthesis, Their Glycosidase Inhibition and Anticancer Properties in View to Boron Neutron Capture Therapy
por: Campkin, David M., et al.
Publicado: (2022)

(4R)-Ethyl 4-(4-chlorophenyl)-2-hydroxy-5-oxo-2,3,4,5-tetrahydropyrano[3,2-c]chromene-2-carboxylate
por: Wang, Yifeng, et al.
Publicado: (2009)

(4R)-Ethyl 4-(4-chlorophenyl)-2-hydroxy-5-oxo-2,3,4,5-tetrahydropyrano[3,2-c]chromene-2-carboxylate. Corrigendum
por: Wang, Yifeng, et al.
Publicado: (2010)

Crystal structure of 4,10-dimethoxy-13-methyl-6H,12H-6,12-epiminodibenzo[b,f][1,5]dioxocine
por: Kasyanova, Katerina V., et al.
Publicado: (2017)

Novel Sophoridine Derivatives Bearing Phosphoramide Mustard Moiety Exhibit Potent Antitumor Activities In Vitro and In Vivo
por: Li, Dongdong, et al.
Publicado: (2018)

3-Hydroxy-4-phenyl-1-(prop-2-en-1-yl)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
por: Rida, Mohamed, et al.
Publicado: (2011)

Synthesis of 6,12-Disubstituted Methanodibenzo[b,f][1,5]dioxocins: Pyrrolidine Catalyzed Self-Condensation of 2′-Hydroxyacetophenones
por: Assoah, Benedicta, et al.
Publicado: (2019)

(Carbazol-9-ido-κN)dichlorido(η(5):η(1)-2,3,4,5-tetramethylpentafulvene)tantalum(V)
por: de Graaff, Simon, et al.
Publicado: (2022)

Synthesis and cytotoxicity evaluation of novel 1,8-acridinedione derivatives bearing phthalimide moiety as potential antitumor agents
por: Khatab, Hassan A., et al.
Publicado: (2023)

Crystal structure and Hirshfeld surface analysis of (4Z)-1-butyl-4-(2-oxopropylidene)-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-one
por: Chkirate, Karim, et al.
Publicado: (2018)

Clicked Cinnamic/Caffeic Esters and Amides as Radical Scavengers and 5-Lipoxygenase Inhibitors
por: Doiron, Jérémie A., et al.
Publicado: (2014)

Kinetics and Threshold Level of 2,3,4,5-Tetrachlorobiphenyl Dechlorination by an Organohalide Respiring Bacterium
por: Lombard, Nathalie J., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_jg2iegfk9v3nnhrrn0osp09cc6