Construction of the 1,2-Dialkenylcyclohexane Framework via Ireland-Claisen Rearrangement and Intramolecular Barbier Reaction: Application to the Synthesis of (±)-Geijerone and a Diastereoisomeric Mixture with Its 5-Epimer

The elemene-type terpenoids, which possess various biological activities, contain a syn- or anti-1,2-dialkenylcyclohexane framework. An efficient synthetic route to the syn- and anti-1,2-dialkenylcyclohexane core and its application in the synthesis of (±)-geijerone and its diastereomer is reported....

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Detalles Bibliográficos
Autores principales: Liang, Dawei, Gao, Nana, Liu, Wei, Dong, Jinhua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271765/
https://www.ncbi.nlm.nih.gov/pubmed/24448064
http://dx.doi.org/10.3390/molecules19011238

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271765/
https://www.ncbi.nlm.nih.gov/pubmed/24448064
http://dx.doi.org/10.3390/molecules19011238

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