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Efficient Synthesis of Kinsenoside and Goodyeroside A by a Chemo-Enzymatic Approach

Kinsenoside (1) and goodyeroside A (2), two naturally occurring stereoisomers with diverse biological activities, have been synthesized efficiently by a chemo-enzymatic approach with a total yield of 12.7%. The aglycones, (R)- and (S)-3-hydroxy-γ-butyrolactone, were prepared from d- and l-malic acid...

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Detalles Bibliográficos
Autores principales: Zhang, Yang, Xia, Yihong, Lai, Yongji, Tang, Fang, Luo, Zengwei, Xue, Yongbo, Yao, Guangmin, Zhang, Yonghui, Zhang, Jinwen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271766/
https://www.ncbi.nlm.nih.gov/pubmed/25340300
http://dx.doi.org/10.3390/molecules191016950