Discovery of New Imidazole Derivatives Containing the 2,4-Dienone Motif with Broad-Spectrum Antifungal and Antibacterial Activity

A compound containing an imidazole moiety and a 2,4-dienone motif with significant activity toward several fungi was discovered in a screen for new antifungal compounds. Then, a total of 26 derivatives of this compound were designed, synthesized and evaluated through in vitro and in vivo antifungal...

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Detalles Bibliográficos
Autores principales: Liu, Chunli, Shi, Ce, Mao, Fei, Xu, Yong, Liu, Jinyan, Wei, Bing, Zhu, Jin, Xiang, Mingjie, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271775/
https://www.ncbi.nlm.nih.gov/pubmed/25268720
http://dx.doi.org/10.3390/molecules191015653

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271775/
https://www.ncbi.nlm.nih.gov/pubmed/25268720
http://dx.doi.org/10.3390/molecules191015653

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