Synthesis and Antifungal Activity of Novel Triazole Compounds Containing Piperazine Moiety

Design and synthesis of triazole library antifungal agents having piperazine side chains, analogues to fluconazole were documented. The synthesis highlighted utilization of the click chemistry on the basis of the active site of the cytochrome P450 14α-demethylase (CYP51). Their structures were chara...

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Detalles Bibliográficos
Autores principales: Wang, Yanwei, Xu, Kehan, Bai, Guojing, Huang, Lei, Wu, Qiuye, Pan, Weihua, Yu, Shichong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271785/
https://www.ncbi.nlm.nih.gov/pubmed/25090121
http://dx.doi.org/10.3390/molecules190811333

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271785/
https://www.ncbi.nlm.nih.gov/pubmed/25090121
http://dx.doi.org/10.3390/molecules190811333

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