Synthesis and Cytotoxic Activity Evaluation of Novel Arylpiperazine Derivatives on Human Prostate Cancer Cell Lines

A series of novel arylpiperazine derivatives was synthesized. The in vitro cytotoxic activities of all synthesized compounds against three human prostate cancer cell lines (PC-3, LNCaP, and DU145) were evaluated by a CCK-8 assay. Compounds 9 and 15 exhibited strong cytotoxic activities against LNCaP...

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Detalles Bibliográficos
Autores principales: Chen, Hong, Liang, Xue, Xu, Fang, Xu, Bingbing, He, Xuelan, Huang, Biyun, Yuan, Mu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271825/
https://www.ncbi.nlm.nih.gov/pubmed/25120056
http://dx.doi.org/10.3390/molecules190812048

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271825/
https://www.ncbi.nlm.nih.gov/pubmed/25120056
http://dx.doi.org/10.3390/molecules190812048

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