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Synthesis and Cytotoxic Activity Evaluation of Novel Arylpiperazine Derivatives on Human Prostate Cancer Cell Lines
A series of novel arylpiperazine derivatives was synthesized. The in vitro cytotoxic activities of all synthesized compounds against three human prostate cancer cell lines (PC-3, LNCaP, and DU145) were evaluated by a CCK-8 assay. Compounds 9 and 15 exhibited strong cytotoxic activities against LNCaP...
Autores principales: | Chen, Hong, Liang, Xue, Xu, Fang, Xu, Bingbing, He, Xuelan, Huang, Biyun, Yuan, Mu |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271825/ https://www.ncbi.nlm.nih.gov/pubmed/25120056 http://dx.doi.org/10.3390/molecules190812048 |
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