Molecular Docking and Fluorescence Characterization of Benzothieno[3,2-d]pyrimidin-4-one Sulphonamide Thio-Derivatives, a Novel Class of Selective Cyclooxygenase-2 Inhibitors

The aims of this study were: (i) to explore the structure-activity relationship of some new anti-inflammatory benzothieno[3,2-d]pyrimidin-4-one sulphonamide thio-derivatives 1–11; and (ii) to evaluate the possibility of using the most active compounds as fluorescent probes to determine tumours or th...

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Detalles Bibliográficos
Autores principales: Barone, Mariarita, Pannuzzo, Giovanna, Santagati, Andrea, Catalfo, Alfio, De Guidi, Guido, Cardile, Venera
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271841/
https://www.ncbi.nlm.nih.gov/pubmed/24830713
http://dx.doi.org/10.3390/molecules19056106

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271841/
https://www.ncbi.nlm.nih.gov/pubmed/24830713
http://dx.doi.org/10.3390/molecules19056106

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