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Three-Component Coupling Reactions of Arynes for the Synthesis of Benzofurans and Coumarins

The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles. Coumarin derivative 5 was formed when diethyl malonate (2) or α-bromomalonate (3) were used as a C2-unit. In contrast, dihydrobenzofu...

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Detalles Bibliográficos
Autores principales: Yoshioka, Eito, Kohtani, Shigeru, Miyabe, Hideto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271845/
https://www.ncbi.nlm.nih.gov/pubmed/24419139
http://dx.doi.org/10.3390/molecules19010863