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Three-Component Coupling Reactions of Arynes for the Synthesis of Benzofurans and Coumarins
The domino three-component coupling reaction of arynes with DMF and active methylenes or methines was studied as a highly efficient method for preparing heterocycles. Coumarin derivative 5 was formed when diethyl malonate (2) or α-bromomalonate (3) were used as a C2-unit. In contrast, dihydrobenzofu...
Autores principales: | Yoshioka, Eito, Kohtani, Shigeru, Miyabe, Hideto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271845/ https://www.ncbi.nlm.nih.gov/pubmed/24419139 http://dx.doi.org/10.3390/molecules19010863 |
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