A Combinatorial Approach to Biophysically Characterise Chemokine-Glycan Binding Affinities for Drug Development

Chemokine binding to glycosaminoglycans (GAGs) is recognised to be an important step in inflammation and other pathological disorders like tumor growth and metastasis. Although different ways and strategies to interfere with these interactions are being pursued, no major breakthrough in the developm...

Descripción completa

Detalles Bibliográficos
Autores principales: Gerlza, Tanja, Hecher, Bianca, Jeremic, Dalibor, Fuchs, Thomas, Gschwandtner, Martha, Falsone, Angelika, Gesslbauer, Bernd, Kungl, Andreas J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271861/
https://www.ncbi.nlm.nih.gov/pubmed/25054442
http://dx.doi.org/10.3390/molecules190710618

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271861/
https://www.ncbi.nlm.nih.gov/pubmed/25054442
http://dx.doi.org/10.3390/molecules190710618

Ejemplares similares