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In Vitro Inhibitory Effects of Scutellarin on Six Human/Rat Cytochrome P450 Enzymes and P-glycoprotein

Inhibition of cytochrome P450 (CYP) and P-glycoprotein (P-gp) are regarded as the most frequent and clinically important pharmacokinetic causes among the various possible factors for drug-drug interactions. Scutellarin is a flavonoid which is widely used for the treatment of cardiovascular diseases....

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Detalles Bibliográficos
Autores principales: Han, Yong-Long, Li, Dan, Yang, Quan-Jun, Zhou, Zhi-Yong, Liu, Li-Ya, Li, Bin, Lu, Jin, Guo, Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271944/
https://www.ncbi.nlm.nih.gov/pubmed/24802986
http://dx.doi.org/10.3390/molecules19055748