Calcium Influx Inhibition is Involved in the Hypotensive and Vasorelaxant Effects Induced by Yangambin

The pharmacological effects on the cardiovascular system of yangambin, a lignan isolated from Ocotea duckei Vattimo (Lauraceae), were studied in rats using combined functional and biochemical approaches. In non-anaesthetized rats, yangambin (1, 5, 10, 20, 30 mg/kg, i.v.) induced hypotension (−3.5 ±...

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Detalles Bibliográficos
Autores principales: Araújo, Islania Giselia Albuquerque, Silva, Darizy Flávia, de Alustau, Maria do Carmo, Dias, Katy Lísias Gondim, Cavalcante, Karla Veruska Marques, Veras, Robson Cavalcante, Barbosa-Filho, José Maria, dos Anjos Neto, Mario, Bendhack, Lusiane Maria, de Azevedo Correia, Nadja, de Medeiros, Isac Almeida
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271947/
https://www.ncbi.nlm.nih.gov/pubmed/24858272
http://dx.doi.org/10.3390/molecules19056863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271947/
https://www.ncbi.nlm.nih.gov/pubmed/24858272
http://dx.doi.org/10.3390/molecules19056863

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