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LC-MS/MS Determination and Pharmacokinetic Study of Dehydrocorydaline in Rat Plasma after Oral Administration of Dehydrocorydaline and Corydalis yanhusuo Extract

A rapid, sensitive and selective liquid chromatography/tandem mass spectrometry method (LC-MS/MS) was developed and validated for determination of dehydrocorydaline (DHC) in rat plasma using nitidine chloride as an internal standard. The analytes were solid-phase extracted and eluted on a C18 chroma...

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Detalles Bibliográficos
Autores principales: Li, Qiu-Yue, Li, Kai-Tong, Sun, Hong, Jin, Wen, Shi, Jia-Wen, Shi, Yue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271950/
https://www.ncbi.nlm.nih.gov/pubmed/25314597
http://dx.doi.org/10.3390/molecules191016312