Structure and Absolute Configuration of 20β-Hydroxyprednisolone, a Biotransformed Product of Predinisolone by the Marine Endophytic Fungus Penicilium lapidosum

The anti-inflammatory drug predinisolone (1) was reduced to 20β-hydroxyprednisolone (2) by the marine endophytic fungus Penicilium lapidosum isolated from an alga. The structural elucidation of 2 was achieved by 1D- and 2D-NMR, MS, IR data. Although, 2 is a known compound previously obtained through...

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Detalles Bibliográficos
Autores principales: Sultan, Sadia, Noor, Muhammad Zaimi bin Mohd, Anouar, El Hassane, Shah, Syed Adnan Ali, Salim, Fatimah, Rahim, Rohani, Trabolsy, Zuhra Bashir Khalifa Al, Weber, Jean-Frédéric Faizal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271985/
https://www.ncbi.nlm.nih.gov/pubmed/25255760
http://dx.doi.org/10.3390/molecules190913775

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6271985/
https://www.ncbi.nlm.nih.gov/pubmed/25255760
http://dx.doi.org/10.3390/molecules190913775

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