Epigenetic biomarkers of promoter DNA methylation in the new era of cancer treatment

Promoter DNA methylation, which occurs on cytosine nucleotides across CpG islands, results in gene silencing and represents a major epigenetic alteration in human cancer. Methylation‐specific PCR can amplify these modifications as markers in cancer cells. In the present work, we rigorously review th...

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Detalles Bibliográficos
Autores principales: Yamashita, Keishi, Hosoda, Kei, Nishizawa, Nobuyuki, Katoh, Hiroshi, Watanabe, Masahiko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Review Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272087/
https://www.ncbi.nlm.nih.gov/pubmed/30264476
http://dx.doi.org/10.1111/cas.13812

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272087/
https://www.ncbi.nlm.nih.gov/pubmed/30264476
http://dx.doi.org/10.1111/cas.13812

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