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Bioavailability Enhancement of Paclitaxel via a Novel Oral Drug Delivery System: Paclitaxel-Loaded Glycyrrhizic Acid Micelles

Paclitaxel (PTX, taxol), a classical antitumor drug against a wide range of tumors, shows poor oral bioavailability. In order to improve the oral bioavailability of PTX, glycyrrhizic acid (GA) was used as the carrier in this study. This was the first report on the preparation, characterization and t...

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Detalles Bibliográficos
Autores principales: Yang, Fu-Heng, Zhang, Qing, Liang, Qian-Ying, Wang, Sheng-Qi, Zhao, Bo-Xin, Wang, Ya-Tian, Cai, Yun, Li, Guo-Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272134/
https://www.ncbi.nlm.nih.gov/pubmed/25756651
http://dx.doi.org/10.3390/molecules20034337