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A Selective G-Quadruplex DNA-Stabilizing Ligand Based on a Cyclic Naphthalene Diimide Derivative

A cyclic naphthalene diimide (cyclic NDI, 1), carrying a benzene moiety as linker chain, was synthesized and its interaction with G-quadruplex DNAs of a-core and a-coreTT as a human telomeric DNA, c-kit and c-myc as DNA sequence at promoter region, or thrombin-binding aptamer (TBA) studied based on...

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Detalles Bibliográficos
Autores principales: Islam, Md. Monirul, Fujii, Satoshi, Sato, Shinobu, Okauchi, Tatsuo, Takenaka, Shigeori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272171/
https://www.ncbi.nlm.nih.gov/pubmed/26076114
http://dx.doi.org/10.3390/molecules200610963