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Synthesis of Peptide Nucleic Acids Containing a Crosslinking Agent and Evaluation of Their Reactivities

Peptide nucleic acids (PNAs) are structural mimics of nucleic acids that form stable hybrids with DNA and RNA. In addition, PNAs can invade double-stranded DNA. Due to these characteristics, PNAs are widely used as biochemical tools, for example, in antisense/antigene therapy. Interstrand crosslink...

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Detalles Bibliográficos
Autores principales: Akisawa, Takuya, Ishizawa, Yuki, Nagatsugi, Fumi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272193/
https://www.ncbi.nlm.nih.gov/pubmed/25781072
http://dx.doi.org/10.3390/molecules20034708