Cargando…
Synthesis of Peptide Nucleic Acids Containing a Crosslinking Agent and Evaluation of Their Reactivities
Peptide nucleic acids (PNAs) are structural mimics of nucleic acids that form stable hybrids with DNA and RNA. In addition, PNAs can invade double-stranded DNA. Due to these characteristics, PNAs are widely used as biochemical tools, for example, in antisense/antigene therapy. Interstrand crosslink...
Autores principales: | Akisawa, Takuya, Ishizawa, Yuki, Nagatsugi, Fumi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272193/ https://www.ncbi.nlm.nih.gov/pubmed/25781072 http://dx.doi.org/10.3390/molecules20034708 |
Ejemplares similares
-
Reactive OFF-ON type alkylating agents for higher-ordered structures of nucleic acids
por: Onizuka, Kazumitsu, et al.
Publicado: (2019) -
Synthesis of 6-Alkynylated Purine-Containing DNA via On-Column Sonogashira Coupling and Investigation of Their Base-Pairing Properties
por: Okamura, Hidenori, et al.
Publicado: (2023) -
Crosslinking reactions of 4-amino-6-oxo-2-vinylpyrimidine with guanine derivatives and structural analysis of the adducts
por: Kusano, Shuhei, et al.
Publicado: (2015) -
Synthesis and structure–activity relationship of peptide nucleic acid probes with improved interstrand-crosslinking abilities: application to biotin-mediated RNA-pulldown
por: Cadoni, Enrico, et al.
Publicado: (2022) -
Formulation of PLGA nanoparticles containing short cationic peptide nucleic acids
por: Malik, Shipra, et al.
Publicado: (2020)