Antibacterial Barbituric Acid Analogues Inspired from Natural 3-Acyltetramic Acids; Synthesis, Tautomerism and Structure and Physicochemical Property-Antibacterial Activity Relationships

The synthesis, tautomerism and antibacterial activity of novel barbiturates is reported. In particular, 3-acyl and 3-carboxamidobarbiturates exhibited antibacterial activity, against susceptible and some resistant Gram-positive strains of particular interest is that these systems possess amenable mo...

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Detalles Bibliográficos
Autores principales: Jeong, Yong-Chul, Moloney, Mark G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272196/
https://www.ncbi.nlm.nih.gov/pubmed/25710842
http://dx.doi.org/10.3390/molecules20033582

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272196/
https://www.ncbi.nlm.nih.gov/pubmed/25710842
http://dx.doi.org/10.3390/molecules20033582

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