Dose-Dependent Cytotoxic Effects of Boldine in HepG-2 Cells—Telomerase Inhibition and Apoptosis Induction

Plant metabolites are valuable sources of novel therapeutic compounds. In an anti-telomerase screening study of plant secondary metabolites, the aporphine alkaloid boldine (1,10-dimethoxy-2,9-dihydroxyaporphine) exhibited a dose and time dependent cytotoxicity against hepatocarcinoma HepG-2 cells. H...

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Detalles Bibliográficos
Autores principales: Kazemi Noureini, Sakineh, Wink, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272231/
https://www.ncbi.nlm.nih.gov/pubmed/25719742
http://dx.doi.org/10.3390/molecules20033730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272231/
https://www.ncbi.nlm.nih.gov/pubmed/25719742
http://dx.doi.org/10.3390/molecules20033730

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