Metabolic Profiling of the Uncaria Hook Alkaloid Geissoschizine Methyl Ether in Rat and Human Liver Microsomes Using High-Performance Liquid Chromatography with Tandem Mass Spectrometry

Geissoschizine methyl ether (GM) is an indole alkaloid found in Uncaria hook, which is a galenical constituent of yokukansan, a traditional Japanese medicine. GM has been identified as the active component responsible for anti-aggressive effects. In this study, the metabolic profiling of GM in rat a...

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Detalles Bibliográficos
Autores principales: Kushida, Hirotaka, Matsumoto, Takashi, Igarashi, Yasushi, Nishimura, Hiroaki, Watanabe, Junko, Maemura, Kazuya, Kase, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272236/
https://www.ncbi.nlm.nih.gov/pubmed/25633336
http://dx.doi.org/10.3390/molecules20022100

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272236/
https://www.ncbi.nlm.nih.gov/pubmed/25633336
http://dx.doi.org/10.3390/molecules20022100

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