Cytotoxicity of the Urokinase-Plasminogen Activator Inhibitor Carbamimidothioic Acid (4-Boronophenyl) Methyl Ester Hydrobromide (BC-11) on Triple-Negative MDA-MB231 Breast Cancer Cells

BC-11 is an easily synthesized simple thiouronium-substituted phenylboronic acid, which has been shown to be cytotoxic on triple negative MDA-MB231 breast cancer cells by inducing a perturbation of cell cycle when administered at a concentration equal to its ED(50) at 72 h (117 μM). Exposure of cell...

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Detalles Bibliográficos
Autores principales: Longo, Alessandra, Librizzi, Mariangela, Chuckowree, Irina S., Baltus, Christine B., Spencer, John, Luparello, Claudio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272237/
https://www.ncbi.nlm.nih.gov/pubmed/26029857
http://dx.doi.org/10.3390/molecules20069879

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272237/
https://www.ncbi.nlm.nih.gov/pubmed/26029857
http://dx.doi.org/10.3390/molecules20069879

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