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Natural Plant Alkaloid (Emetine) Inhibits HIV-1 Replication by Interfering with Reverse Transcriptase Activity

Ipecac alkaloids are secondary metabolites produced in the medicinal plant Psychotria ipecacuanha. Emetine is the main alkaloid of ipecac and one of the active compounds in syrup of Ipecac with emetic property. Here we evaluated emetine’s potential as an antiviral agent against Human Immunodeficienc...

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Detalles Bibliográficos
Autores principales: Valadão, Ana Luiza Chaves, Abreu, Celina Monteiro, Dias, Juliana Zanatta, Arantes, Pablo, Verli, Hugo, Tanuri, Amilcar, de Aguiar, Renato Santana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272240/
https://www.ncbi.nlm.nih.gov/pubmed/26111177
http://dx.doi.org/10.3390/molecules200611474