LC-MS/MS Determination and Pharmacokinetic Study of Pedunculoside in Rat Plasma after Oral Administration of Pedunculoside and Ilex rotunda Extract

Ilex rotunda is widely used to treat many disorders as a traditional Chinese medicine (TCM) containing 4%–5% pedunculoside (PDC). A rapid, selective, and sensitive liquid chromatography-tandem mass spectrometry method (LC-MS/MS) was developed and validated to determine PDC in rat plasma by using 3β,...

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Detalles Bibliográficos
Autores principales: Zhao, Waiou, Pang, Li, Xu, Dahai, Zhang, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272306/
https://www.ncbi.nlm.nih.gov/pubmed/25996213
http://dx.doi.org/10.3390/molecules20059084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272306/
https://www.ncbi.nlm.nih.gov/pubmed/25996213
http://dx.doi.org/10.3390/molecules20059084

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