Cargando…

LC-MS/MS Determination and Pharmacokinetic Study of Pedunculoside in Rat Plasma after Oral Administration of Pedunculoside and Ilex rotunda Extract

Ilex rotunda is widely used to treat many disorders as a traditional Chinese medicine (TCM) containing 4%–5% pedunculoside (PDC). A rapid, selective, and sensitive liquid chromatography-tandem mass spectrometry method (LC-MS/MS) was developed and validated to determine PDC in rat plasma by using 3β,...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Waiou, Pang, Li, Xu, Dahai, Zhang, Nan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272306/ https://www.ncbi.nlm.nih.gov/pubmed/25996213 http://dx.doi.org/10.3390/molecules20059084

Ejemplares similares

Pedunculoside protects against LPS-induced mastitis in mice by inhibiting inflammation and maintaining the integrity of blood-milk barrier
por: Kan, Xingchi, et al.
Publicado: (2021)

A Water-Soluble Inclusion Complex of Pedunculoside with the Polymer β-Cyclodextrin: A Novel Anti-Inflammation Agent with Low Toxicity
por: Liu, Chang, et al.
Publicado: (2014)

LC-MS/MS Determination and Pharmacokinetic Study of Dehydrocorydaline in Rat Plasma after Oral Administration of Dehydrocorydaline and Corydalis yanhusuo Extract
por: Li, Qiu-Yue, et al.
Publicado: (2014)

Simultaneous Determination of Columbianadin and Its Metabolite Columbianetin in Rat Plasma by LC-MS/MS: Application to Pharmacokinetics of Columbianadin after Oral Administration
por: Li, Jin, et al.
Publicado: (2018)

LC-MS/MS determination and pharmacokinetics study of puerarin and daidzein in rat plasma after oral administration of Gegenqinlian decoction and Radix Puerariae extract
por: Zhang, Yifan, et al.
Publicado: (2014)

LC–MS/MS determination and pharmacokinetic study of columbianadin in rat plasma after intravenous administration of pure columbianadin
por: Chang, Yan-xu, et al.
Publicado: (2014)

Determination and pharmacokinetics study of UK-5099 in mouse plasma by LC–MS/MS
por: Zeng, Qingyuan, et al.
Publicado: (2022)

Determination of myrislignan levels in BALB/c mouse plasma by LC-MS/MS and a comparison of its pharmacokinetics after oral and intraperitoneal administration
por: Zhang, Jili, et al.
Publicado: (2021)

LC-MS/MS determination of avanafil and its metabolites in rat plasma and brain: pharmacokinetic study after oral administration and transdermal film application
por: Kammoun, Ahmed K., et al.
Publicado: (2020)

A Pharmacokinetic Study of Ephedrine and Pseudoephedrine after Oral Administration of Ojeok-San by Validated LC-MS/MS Method in Human Plasma
por: Lee, Sooyoung, et al.
Publicado: (2021)

Largazole Pharmacokinetics in Rats by LC-MS/MS
por: Yu, Mingming, et al.
Publicado: (2014)

Pharmacokinetic Studies of Three Alkaloids in Rats After Intragastrical Administration of Lycopodii Herba Extract by LC-MS/MS
por: Ma, Dongke, et al.
Publicado: (2019)

LC–MS/MS determination and pharmacokinetic study of bergenin, the main bioactive component of Bergenia purpurascens after oral administration in rats
por: Li, Bao-Hong, et al.
Publicado: (2013)

Simultaneous Determination of Atorvastatin and Aspirin in Human Plasma by LC–MS/MS: Its Pharmacokinetic Application
por: Gajula, Ramakrishna, et al.
Publicado: (2012)

Determination of dihydromyricetin in rat plasma by LC-MS/MS and its application to a pharmacokinetic study
por: Liu, Lu, et al.
Publicado: (2016)

Determination of cepharanthine in rat plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Deng, Yingbin, et al.
Publicado: (2017)

Bioequivalance and pharmacokinetic study of febuxostat in human plasma by using LC-MS/MS with liquid liquid extraction method
por: Chandu, Babu Rao, et al.
Publicado: (2013)

UHPLC-MS/MS Determination, Pharmacokinetic, and Bioavailability Study of Taxifolin in Rat Plasma after Oral Administration of its Nanodispersion
por: Yang, Chun-Juan, et al.
Publicado: (2016)

Determination of Leuprolide–Fatty Acid Conjugate in Rat Plasma Using LC-MS/MS and Its Pharmacokinetics after Subcutaneous Administration in Rats
por: Seong, Gi-Sang, et al.
Publicado: (2022)

Determination and Pharmacokinetic Study of Gentiopicroside, Geniposide, Baicalin, and Swertiamarin in Chinese Herbal Formulae after Oral Administration in Rats by LC-MS/MS
por: Lu, Chia-Ming, et al.
Publicado: (2014)

Determination and pharmacokinetics study of oxyclozanide suspension in cattle by LC-MS/MS
por: Zhang, Jili, et al.
Publicado: (2019)

Quantification of tolvaptan in rabbit plasma by LC–MS/MS: Application to a pharmacokinetic study()
por: Moola, Kumar S., et al.
Publicado: (2015)

The LC-MS/MS-Based Measurement of Isopimaric Acid in Rat Plasma and Application of Pharmacokinetics
por: Huang, Doudou, et al.
Publicado: (2021)

Rapid and Sensitive Determination of Timosaponin AIII in Rat Plasma by LC-MS/MS and Its Pharmacokinetic Application
por: Liu, Yanping, et al.
Publicado: (2013)

Precolumn derivatization LC–MS/MS method for the determination and pharmacokinetic study of glucosamine in human plasma and urine
por: Song, Min, et al.
Publicado: (2012)

Validated LC-MS/MS Method for the Determination of Scopoletin in Rat Plasma and Its Application to Pharmacokinetic Studies
por: Zeng, Yingchun, et al.
Publicado: (2015)

Establishment of LC-MS/MS Method for Determination of GMDTC in Rat Plasma and Its Application in Preclinical Pharmacokinetics
por: Hu, Wei, et al.
Publicado: (2023)

Identification of the Chemical Constituents in Simiao Wan and Rat Plasma after Oral Administration by GC-MS and LC-MS
por: Fan, Yunshuang, et al.
Publicado: (2017)

A validated LC–MS/MS method for clinical pharmacokinetics and presumptive phase II metabolic pathways following oral administration of Andrographis paniculata extract
por: Songvut, Phanit, et al.
Publicado: (2023)

Determination of the Pharmacokinetics and Oral Bioavailability of Salicylamine, a Potent γ-Ketoaldehyde Scavenger, by LC/MS/MS
por: Zagol-Ikapitte, Irene, et al.
Publicado: (2010)

Ultrasound-Assisted Extraction of Syringin from the Bark of Ilex rotunda Thumb Using Response Surface Methodology
por: Zhao, Li-Chun, et al.
Publicado: (2012)

Simultaneous Determination and Pharmacokinetic Study of Six Components in Rat Plasma by HPLC-MS/MS after Oral Administration of Acanthopanax sessiliflorus Fruit Extract
por: Du, Peng, et al.
Publicado: (2016)

Simultaneous Determination and Pharmacokinetics Study of Six Triterpenes in Rat Plasma by UHPLC-MS/MS after Oral Administration of Sanguisorba officinalis L. Extract
por: Wu, Chengcui, et al.
Publicado: (2018)

Determination and Pharmacokinetic Study of Three Diterpenes in Rat Plasma by UHPLC-ESI-MS/MS after Oral Administration of Rosmarinus officinalis L. Extract
por: Wang, Liqian, et al.
Publicado: (2017)

Bioanalytical Method for Carbocisteine in Human Plasma by Using LC-MS/MS: A Pharmacokinetic Application
por: Dhanure, Shivanand, et al.
Publicado: (2014)

Quantification of desloratadine in human plasma by LC-ESI-MS/MS and application to a pharmacokinetic study
por: Ponnuru, Venkata Suresh, et al.
Publicado: (2012)

Simultaneous determination of acetaminophen and oxycodone in human plasma by LC–MS/MS and its application to a pharmacokinetic study
por: Lu, Wei, et al.
Publicado: (2018)

Determination of Epimedin B in Rat Plasma and Tissue by LC-MS/MS: Application in Pharmacokinetic and Tissue Distribution Studies
por: Feng, Qianru, et al.
Publicado: (2017)

Development, Validation of LC-MS/MS Method and Determination of Pharmacokinetic Parameters of the Stroke Neuroprotectant Neurounina-1 in Beagle Dog Plasma After Intravenous Administration
por: Severino, Beatrice, et al.
Publicado: (2019)

Analysis of Antioxidant Constituents from Ilex rotunda and Evaluation of Their Blood–Brain Barrier Permeability
por: Kim, Chang-Kwon, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_aj8tkvnknv3kv2ap1mku3qq09a