Economical Synthesis of (13)C-Labeled Opiates, Cocaine Derivatives and Selected Urinary Metabolites by Derivatization of the Natural Products

The illegal use of opiates and cocaine is a challenge world-wide, but some derivatives are also valuable pharmaceuticals. Reference samples of the active ingredients and their metabolites are needed both for controlling administration in the clinic and to detect drugs of abuse. Especially, (13)C-lab...

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Detalles Bibliográficos
Autores principales: Karlsen, Morten, Liu, Huiling, Johansen, Jon Eigill, Hoff, Bård Helge
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272324/
https://www.ncbi.nlm.nih.gov/pubmed/25816077
http://dx.doi.org/10.3390/molecules20045329