Synthesis and in Vitro Screening of Phenylbipyridinylpyrazole Derivatives as Potential Antiproliferative Agents

A series of phenylbipyridinylpyrazoles was synthesized through the reaction of 2-(4-(2-chloropyridin-4-yl)-3-(3-methoxy-5-methylphenyl)-1H-pyrazol-1-yl)acetonitrile (4) with different 6-substituted pyridine-3-ylboronic acids. The final compounds 5a–j were screened at 10 µM against over 60 tumor cell...

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Detalles Bibliográficos
Autores principales: Al-Sanea, Mohammad M., Elkamhawy, Ahmed, Zakaria, Ahmed, Park, Byung Sun, Kwon, Youngjoo, Lee, So Ha, Lee, Sang Woo, Kim, In Tae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272331/
https://www.ncbi.nlm.nih.gov/pubmed/25584833
http://dx.doi.org/10.3390/molecules20011031

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272331/
https://www.ncbi.nlm.nih.gov/pubmed/25584833
http://dx.doi.org/10.3390/molecules20011031

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