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Synthesis and QSAR Study of Novel 6-Chloro-3-(2-Arylmethylene-1-methylhydrazino)-1,4,2-benzodithiazine 1,1-Dioxide Derivatives with Anticancer Activity

A series of new 6-chloro-3-(2-arylmethylene-1-methylhydrazino)-1,4,2-benzodithiazine 1,1-dioxide derivatives were effectively synthesized from N-methyl-N-(6-chloro-1,1-dioxo-1,4,2-benzodithiazin-3-yl)hydrazines. The intermediate compounds as well as the products, were evaluated for their cytotoxic e...

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Detalles Bibliográficos
Autores principales: Sławiński, Jarosław, Żołnowska, Beata, Brzozowski, Zdzisław, Kawiak, Anna, Belka, Mariusz, Bączek, Tomasz
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272346/
https://www.ncbi.nlm.nih.gov/pubmed/25834988
http://dx.doi.org/10.3390/molecules20045754