NBM-T-BBX-OS01, Semisynthesized from Osthole, Induced G1 Growth Arrest through HDAC6 Inhibition in Lung Cancer Cells

Disrupting lung tumor growth via histone deacetylases (HDACs) inhibition is a strategy for cancer therapy or prevention. Targeting HDAC6 may disturb the maturation of heat shock protein 90 (Hsp90) mediated cell cycle regulation. In this study, we demonstrated the effects of semisynthesized NBM-T-BBX...

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Detalles Bibliográficos
Autores principales: Pai, Jih-Tung, Hsu, Chia-Yun, Hua, Kuo-Tai, Yu, Sheng-Yung, Huang, Chung-Yang, Chen, Chia-Nan, Liao, Chiung-Ho, Weng, Meng-Shih
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272357/
https://www.ncbi.nlm.nih.gov/pubmed/25946558
http://dx.doi.org/10.3390/molecules20058000

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272357/
https://www.ncbi.nlm.nih.gov/pubmed/25946558
http://dx.doi.org/10.3390/molecules20058000

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