Neferine Attenuates the Protein Level and Toxicity of Mutant Huntingtin in PC-12 Cells via Induction of Autophagy

Mutant huntingtin aggregation is highly associated with the pathogenesis of Huntington’s disease, an adult-onset autosomal dominant disorder, which leads to a loss of motor control and decline in cognitive function. Recent literature has revealed the protective role of autophagy in neurodegenerative...

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Detalles Bibliográficos
Autores principales: Wong, Vincent Kam Wai, Wu, An Guo, Wang, Jing Rong, Liu, Liang, Law, Betty Yuen-Kwan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272412/
https://www.ncbi.nlm.nih.gov/pubmed/25699594
http://dx.doi.org/10.3390/molecules20033496

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272412/
https://www.ncbi.nlm.nih.gov/pubmed/25699594
http://dx.doi.org/10.3390/molecules20033496

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