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Synthesis of Novel Dihydropyridothienopyrimidin-4,9-dione Derivatives

A novel molecular scaffold, dihydropyridothienopyrimidin-4,9-dione, was synthesized from benzylamine or p-methoxybenzylamine in six steps involving successive ring closure to form a fused ring system composed of dihydropyridone, thiophene and pyrimidone. The pharmacological versatility of the dihydr...

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Detalles Bibliográficos
Autores principales: Kim, Youngjae, Kim, Minjoo, Park, Mooseong, Tae, Jinsung, Baek, Du-Jong, Park, Ki Duk, Choo, Hyunah
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272423/
https://www.ncbi.nlm.nih.gov/pubmed/25808151
http://dx.doi.org/10.3390/molecules20035074