Synthesis, (18)F-Radiolabelling and Biological Characterization of Novel Fluoroalkylated Triazine Derivatives for in Vivo Imaging of Phosphodiesterase 2A in Brain via Positron Emission Tomography

Phosphodiesterase 2A (PDE2A) is highly and specifically expressed in particular brain regions that are affected by neurological disorders and in certain tumors. Development of a specific PDE2A radioligand would enable molecular imaging of the PDE2A protein via positron emission tomography (PET). Her...

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Detalles Bibliográficos
Autores principales: Schröder, Susann, Wenzel, Barbara, Deuther-Conrad, Winnie, Teodoro, Rodrigo, Egerland, Ute, Kranz, Mathias, Scheunemann, Matthias, Höfgen, Norbert, Steinbach, Jörg, Brust, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272448/
https://www.ncbi.nlm.nih.gov/pubmed/26016549
http://dx.doi.org/10.3390/molecules20069591

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272448/
https://www.ncbi.nlm.nih.gov/pubmed/26016549
http://dx.doi.org/10.3390/molecules20069591

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