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The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity
Amyloidosis is a protein folding disorder in which normally soluble proteins are deposited extracellularly as insoluble fibrils, impairing tissue structure and function. Charged polyelectrolytes such as glycosaminoglycans (GAGs) are frequently found associated with the proteinaceous deposits in tiss...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272481/ https://www.ncbi.nlm.nih.gov/pubmed/25648594 http://dx.doi.org/10.3390/molecules20022510 |