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The Effect of Glycosaminoglycans (GAGs) on Amyloid Aggregation and Toxicity

Amyloidosis is a protein folding disorder in which normally soluble proteins are deposited extracellularly as insoluble fibrils, impairing tissue structure and function. Charged polyelectrolytes such as glycosaminoglycans (GAGs) are frequently found associated with the proteinaceous deposits in tiss...

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Detalles Bibliográficos
Autores principales: Iannuzzi, Clara, Irace, Gaetano, Sirangelo, Ivana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272481/
https://www.ncbi.nlm.nih.gov/pubmed/25648594
http://dx.doi.org/10.3390/molecules20022510

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