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Molecular Cloning, Carbohydrate Specificity and the Crystal Structure of Two Sclerotium rolfsii Lectin Variants

SRL is a cell wall associated developmental-stage specific lectin secreted by Sclerotium rolfsii, a soil-born pathogenic fungus. SRL displays specificity for TF antigen (Galβ1→3GalNAc-α-Ser//Thr) expressed in all cancer types and has tumour suppressing effects in vivo. Considering the immense potent...

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Detalles Bibliográficos
Autores principales: Peppa, Vassiliki I., Venkat, Hemalatha, Kantsadi, Anastassia L., Inamdar, Shashikala R., Bhat, Ganapati G., Eligar, Sachin, Shivanand, Anupama, Chachadi, Vishwanath B., Satisha, Gonchigar J., Swamy, Bale M., Skamnaki, Vassiliki T., Zographos, Spyridon E., Leonidas, Demetres D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272482/
https://www.ncbi.nlm.nih.gov/pubmed/26076107
http://dx.doi.org/10.3390/molecules200610848