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Development of a Novel Antimicrobial Screening System Targeting the Pyoverdine-Mediated Iron Acquisition System and Xenobiotic Efflux Pumps

The iron acquisition systems in Pseudomonas aeruginosa are inducible in response to low-iron conditions and important for growth of this organism under iron limitation. OprM is the essential outer membrane subunit of the MexAB-OprM xenobiotic efflux pump. We designed and constructed a new model anti...

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Detalles Bibliográficos
Autores principales: Sato, Kazuki, Ushioda, Kenichi, Akiba, Keiji, Matsumoto, Yoshimi, Maseda, Hideaki, Ando, Tasuke, Isogai, Emiko, Nakae, Taiji, Yoneyama, Hiroshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272503/
https://www.ncbi.nlm.nih.gov/pubmed/25939068
http://dx.doi.org/10.3390/molecules20057790