Isoindolinones as Michael Donors under Phase Transfer Catalysis: Enantioselective Synthesis of Phthalimidines Containing a Tetrasubstituted Carbon Stereocenter

Readily available chiral ammonium salts derived from cinchona alkaloids have proven to be effective phase transfer catalysts in the asymmetric Michael reaction of 3-substituted isoindolinones. This protocol provides a convenient method for the construction of valuable asymmetric 3,3-disubstituted is...

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Detalles Bibliográficos
Autores principales: Scorzelli, Francesco, Di Mola, Antonia, Palombi, Laura, Massa, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272520/
https://www.ncbi.nlm.nih.gov/pubmed/25985353
http://dx.doi.org/10.3390/molecules20058484

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272520/
https://www.ncbi.nlm.nih.gov/pubmed/25985353
http://dx.doi.org/10.3390/molecules20058484

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