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Isoindolinones as Michael Donors under Phase Transfer Catalysis: Enantioselective Synthesis of Phthalimidines Containing a Tetrasubstituted Carbon Stereocenter

Readily available chiral ammonium salts derived from cinchona alkaloids have proven to be effective phase transfer catalysts in the asymmetric Michael reaction of 3-substituted isoindolinones. This protocol provides a convenient method for the construction of valuable asymmetric 3,3-disubstituted is...

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Detalles Bibliográficos
Autores principales:	Scorzelli, Francesco, Di Mola, Antonia, Palombi, Laura, Massa, Antonio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272520/ https://www.ncbi.nlm.nih.gov/pubmed/25985353 http://dx.doi.org/10.3390/molecules20058484

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