Inhibition of the NF-κB Signaling Pathway by a Novel Heterocyclic Curcumin Analogue

In this study a series of curcumin analogues were evaluated for their ability to inhibit the activation of NF-κΒ, a transcription factor at the crossroads of cancer-inflammation. Our novel curcumin analogue BAT3 was identified to be the most potent NF-κB inhibitor and EMSA assays clearly showed inhi...

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Detalles Bibliográficos
Autores principales: Katsori, Anna-Maria, Palagani, Ajay, Bougarne, Nadia, Hadjipavlou-Litina, Dimitra, Haegeman, Guy, Vanden Berghe, Wim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272537/
https://www.ncbi.nlm.nih.gov/pubmed/25580684
http://dx.doi.org/10.3390/molecules20010863

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272537/
https://www.ncbi.nlm.nih.gov/pubmed/25580684
http://dx.doi.org/10.3390/molecules20010863

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