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Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus(®)

Solid dispersions are a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). The aim of this study was to improve the physicochemical properties and bioavailability of a poorly water-soluble aprepitant by preparation of...

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Detalles Bibliográficos
Autores principales: Liu, Jinwen, Zou, Meijuan, Piao, Hongyu, Liu, Yi, Tang, Bo, Gao, Ying, Ma, Ning, Cheng, Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272549/
https://www.ncbi.nlm.nih.gov/pubmed/26102068
http://dx.doi.org/10.3390/molecules200611345