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Characterization and Pharmacokinetic Study of Aprepitant Solid Dispersions with Soluplus(®)
Solid dispersions are a useful approach to improve the dissolution rate and bioavailability of poorly water-soluble active pharmaceutical ingredients (APIs). The aim of this study was to improve the physicochemical properties and bioavailability of a poorly water-soluble aprepitant by preparation of...
Autores principales: | Liu, Jinwen, Zou, Meijuan, Piao, Hongyu, Liu, Yi, Tang, Bo, Gao, Ying, Ma, Ning, Cheng, Gang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272549/ https://www.ncbi.nlm.nih.gov/pubmed/26102068 http://dx.doi.org/10.3390/molecules200611345 |
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