Cargando…

Culture Conditions Affect Expression of DUX4 in FSHD Myoblasts

Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of double homeobox 4 (DUX4) due to epigenetic changes of the D4Z4 region at chromosome 4q35. Detecting DUX4 is challenging due to its stochastic expression pattern and low transcription level. In this study...

Descripción completa

Detalles Bibliográficos
Autores principales: Pandey, Sachchida Nand, Khawaja, Hunain, Chen, Yi-Wen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272558/
https://www.ncbi.nlm.nih.gov/pubmed/26007167
http://dx.doi.org/10.3390/molecules20058304