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Culture Conditions Affect Expression of DUX4 in FSHD Myoblasts

Facioscapulohumeral muscular dystrophy (FSHD) is believed to be caused by aberrant expression of double homeobox 4 (DUX4) due to epigenetic changes of the D4Z4 region at chromosome 4q35. Detecting DUX4 is challenging due to its stochastic expression pattern and low transcription level. In this study...

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Detalles Bibliográficos
Autores principales:	Pandey, Sachchida Nand, Khawaja, Hunain, Chen, Yi-Wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2015
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272558/ https://www.ncbi.nlm.nih.gov/pubmed/26007167 http://dx.doi.org/10.3390/molecules20058304

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