Cargando…

Synthesis and Biological Evaluation of Novel 6-Hydroxy-benzo[d][1,3]oxathiol-2-one Schiff Bases as Potential Anticancer Agents

With the aim of discovering new anticancer agents, we have designed and synthesized novel 6-hydroxy-benzo[d][1,3]oxathiol-2-one Schiff bases. The synthesis started with the selective nitration at 5-position of 6-hydroxybenzo[d][1,3]oxathiol-2-one (1) leading to the nitro derivative 2. The nitro grou...

Descripción completa

Detalles Bibliográficos
Autores principales: Chazin, Eliza de Lucas, Sanches, Paola de Souza, Lindgren, Eric Brazil, Vellasco Júnior, Walcimar Trindade, Pinto, Laine Celestino, Burbano, Rommel Mario Rodríguez, Yoneda, Julliane Diniz, Leal, Kátia Zaccur, Gomes, Claudia Regina Brandão, Wardell, James Lewis, Wardell, Solange Maria Silva Veloso, Montenegro, Raquel Carvalho, Vasconcelos, Thatyana Rocha Alves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272564/
https://www.ncbi.nlm.nih.gov/pubmed/25633329
http://dx.doi.org/10.3390/molecules20021968