Surfing the Protein-Protein Interaction Surface Using Docking Methods: Application to the Design of PPI Inhibitors

Blocking protein-protein interactions (PPI) using small molecules or peptides modulates biochemical pathways and has therapeutic significance. PPI inhibition for designing drug-like molecules is a new area that has been explored extensively during the last decade. Considering the number of available...

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Detalles Bibliográficos
Autores principales: Sable, Rushikesh, Jois, Seetharama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2015
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272567/
https://www.ncbi.nlm.nih.gov/pubmed/26111183
http://dx.doi.org/10.3390/molecules200611569

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6272567/
https://www.ncbi.nlm.nih.gov/pubmed/26111183
http://dx.doi.org/10.3390/molecules200611569

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